THE “MORNING CLLOID TIDE” AS WE CALL IT

Take two NSAIDs and call on your satellite cells in the morning IT IS GENERALLY AGREED

IT IS GENERALLY AGREED that successful skeletal muscle regeneration following intense exercise or injury is facilitated by the protein synthesis machinery and the recruitment of myogenic stem (satellite) cells. Upstream activation of these processes, however, is poorly understood. A growing body of evidence suggests cyclooxygenase (COX) activity plays an important role, as COX inhibition via no...

Life as we know it

This paper presents a heuristic proof (and simulations of a primordial soup) suggesting that life-or biological self-organization-is an inevitable and emergent property of any (ergodic) random dynamical system that possesses a Markov blanket. This conclusion is based on the following arguments: if the coupling among an ensemble of dynamical systems is mediated by short-range forces, then the st...

Gender and sleep "Morning came, as it always does".

The ‘novel’ influenza A(H1N1) enigma: is it a pandemic, how should we respond, what should we call it?

On 24 April 2009 the World Health Organization (WHO) reported human cases of swine influenza A ⁄H1N1 occurring in the USA and Mexico. The number of recorded cases increased rapidly, there was clear human to human transmission, and it appears that the outbreak originated in Mexico in mid-March or earlier. This prompted WHO on 27th April to raise its pandemic preparedness from phase three, where ...

Assessing the Health Impact of Trade: A Call for an Expanded Research Agenda; Comment on “The Trans-Pacific Partnership: Is It Everything We Feared for Health?”

Labonté et al provide an insightful analysis of the Trans-Pacific Partnership (TPP) and its impact on a selection of important health determinants. Their work confirms concerns raised by previous analyses of leaked drafts and offers governments serious and timely reasons to carefully consider provisions of the agreement prior to moving forward with ratification. It also contributes more general...